The Ollipsis 

Questions and Answers

To protect all participants, the FDA has certain eligibility criteria for egg donors. Your eligibility is determined by a series of physical and psychological tests per the FDA’s guidelines.

You will be asked to fill out a pre-screen questionnaire about personal and family medical history. A fertility doctor will conduct a physical exam and laboratory tests, while a fertility psychologist will help ensure that you fully understand your options and what it means to donate your eggs to another family. To be considered eligible, you also consent to donate half of your retrieved eggs.

If you are not eligible, our commitment to you is that we will provide you with the same guidance we give to eligible donors to embark on your fertility journey.

You have at least two other options if you choose to proceed with egg freezing outside of our program: you can pay for the egg freezing cycle out of pocket or you can secure a loan from one of several companies specializing in loans for fertility treatments.

We will help you understand your options and support you in whichever decision you make.

The pre-screen questionnaire will ask about your family and your medical history, current health condition, and interest in becoming a donor. You can access the form by clicking here.

There will be four primary tests used to evaluate your fertility health and eligibility for the procedure.  Click on each link to learn more about what to expect: Psychological, Physical, Clinical, Genetic.

The number of eggs retrieved varies from patient to patient and even across different cycles with the same patient. Moreover, various studies show different averages and medians across populations.

We can safely estimate that for healthy women ages 25 to 32, somewhere between 9 and 23 eggs will be retrieved. The number of eggs retrieved is consistently lowered with age.
You will keep half of the total number of retrieved mature eggs for your future use and donate the other half.

We are committed to splitting the number of retrieved mature eggs in half regardless of the number of eggs retrieved.

It depends on the number of mature eggs retrieved. If 12 mature eggs are retrieved, 6 will be donated. The probability of one live birth from 6 mature eggs is ~50%, two live births ~14%, and
three live births ~2%. If 14 mature eggs are retrieved, 7 will be donated. The chance of one live birth from 7 mature eggs is ~56%, two live births ~18%, and three live births ~3%.

The full procedure, from the first hormonal medication until retrieval, typically takes between 10 and 15 days. We will check in with you at least every other day as you undergo daily hormone injections to stimulate the ovaries, which will take 10-14 days.

On retrieval day you will undergo a 15-minute outpatient surgical procedure. The surgery is minimally invasive, and most women are able to return to their normal activities the next day.

By moving forward with Ollipsis, you understand that you are donating half of your eggs. However, if you do change your mind about the donation requirement, you may do so up until the retrieval step, in which case you must pay for all services rendered and any future services.

Retrieved eggs undergo various screenings and processes before they are ready for insemination; at each stage, a number of eggs will not make it.

This process is called the “egg freezing funnel.” To increase your chances for one or more live births, we recommend banking at least 16 to 20 eggs before the age of 35, which may require more than one cycle of egg freezing.
Research has shown that eggs frozen for over five years show no difference in fertilization rate, clinical pregnancy rate, or ongoing pregnancy rate to those frozen for 6 months…

The current record for the longest storage period resulting in a live birth is 14 years!

Over the course of the procedure, from hormonal medication to retrieval, some women may experience mild PMS symptoms, such as bloating, fatigue, breast tenderness, or mood swings.
However, these are unlikely to impact daily life, and most women report feeling complete back to normal after their first-period post-retrieval, which generally occurs one week later.

The majority of women will not experience side effects while undergoing egg preservation; for those that do, the effects are minor and short-term. Occasionally, ovarian stimulation hormone injections can lead to OHSS, ovarian hyperstimulation syndrome, which causes the ovaries to swell and can be painful. However, under current protocols, this risk is very low. Studies done so far have found no evidence of longer-term health risks associated with egg freezing, and your fertility will not be impacted.

Extensive research has found similar results in the risk of pregnancy complications, or birth defects and chromosomal anomalies. However, it’s important to be aware of obstetric risks that may arise from pregnancy at older ages, such as pre-eclampsia, high blood pressure, gestational diabetes, or preterm delivery. When planning for parenthood, it’s also useful to consider the socioeconomic consequences of becoming a parent at a later age, such as between 50 and 60 (thanks to vitrification, more and more women are experiencing pregnancies at these ages).

No, egg freezing, and ovarian stimulation more generally (e.g. for in vitro fertilization) does not change a woman’s risk of breast cancer, which can vary depending on genetics, lifestyle, etc. A landmark study of across 21 years of 25,000 women who had undergone ovarian stimulation found the same risks of breast cancer as the general population.

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